The sign you mentioned, Symbol Note 1010-64, is the "No Entry" sign. This circular sign with a red border and a white horizontal bar indicates that all vehicles are prohibited from entering a particular road or area. It is typically used at the entrance of one-way streets to prevent vehicles from entering the wrong way, as well as in areas where access is restricted for safety or legal reasons.
Drivers must respect this sign and should not proceed past it, as entering can lead to accidents or legal penalties. Always pay attention to additional signage that may provide context for the entry prohibition.