What are the possible consequences if the wheel nuts are not re-tightened following a tyre change?

If wheel nuts are not properly re-tightened after changing a tyre, there are serious safety risks. Firstly, the wheel can become damaged from movement against the hub. More dangerously, the wheel can work itself loose and detach from the vehicle while driving, which can cause loss of control and an accident. The tyre itself cannot detach from the hub independently; it is the whole wheel that may detach. This is why answers 1 and 2 are correct. Always re-tighten wheel nuts after a tyre change to ensure your safety and the safety of others on the road.